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MITOGEN-ACTIVATED PROTEIN KINASE KINASES
Descriptors Found:
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DeCS
Descriptor
English
:
Mitogen-Activated Protein Kinase Kinases
Descriptor
Spanish
:
Quinasas de Proteína Quinasa Mitógeno Activadas
Descriptor
Portuguese
:
Quinases de Proteína Quinase Ativadas por Mitógeno
Synonyms
English
:
MAP Kinase Kinases
MAPK Kinases
MAPK-ERK Kinases
MAPKKs
MEKs
Tree Number:
D08.811.913.696.620.682.700.565
D08.811.913.696.620.682.725.200
D12.644.360.440
D12.776.476.440
Definition
English
:
A serine-threonine protein kinase
family
whose members are components in protein kinase cascades activated by diverse stimuli. These MAPK kinases phosphorylate
MITOGEN-ACTIVATED PROTEIN KINASES
and are themselves phosphorylated by
MAP KINASE KINASE KINASES
. JNK kinases (also known as SAPK kinases) are a subfamily.
See Related
English
:
MAP Kinase Signaling System
History Note
English
:
2000; for MAP-ERK KINASE use MEK1 PROTEIN (NM) 1992-1999
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
34449
Unique Identifier:
D020929
Occurrence in VHL
:
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